IKK alpha anticorps

N° du produit ABIN966383

L’anticorps Lapin Polyclonal anti-IKK alpha a été validé pour IHC. Il convient pour détecter IKK alpha dans des échantillons de Humain, Souris et Rat. Il y a 2+ publications disponibles.

Aperçu rapide pour IKK alpha anticorps (ABIN966383)

Antigène: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IKK alpha est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-IKK alpha anticorps

Specificité: IKK (Ab-23) Antibody detects endogenous levels of total IKK protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human IKK around the phosphorylation site of Threonine 23 (L-G-TP-G-G).

Information d'application

Indications d'application: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-IKK alpha (ABIN966383)

Yuan, Feldman, Sun, Olashaw, Coppola, Sussman, Shelley, Nicosia, Cheng: "Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells." dans: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 29973-82, (2002) (PubMed).

Ozes, Mayo, Gustin, Pfeffer, Pfeffer, Donner: "NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase." dans: Nature, Vol. 401, Issue 6748, pp. 82-5, (1999) (PubMed).

Détails sur IKK alpha

Antigène: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Autre désignation: IKK alpha

Pathways: Signalisation PI3K-Akt, Signalisation NF-kappaB, Signalisation RTK, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins